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In vivo, carbon-labeled acetate from fermentation in the gut was shown to transverse into the brain by crossing the BBB, upon which it is utilized by hypothalamic neurons for the generation of GABA and lactate [193]
But the contraindicated populations we do know include: Pregnant or nursing individuals : The safety of BPC-157 in pregnant or nursing individuals hasnt been established or investigated in research
Respir Res 12 , 133 (2011)
Recent clinical trials(Hardan et al., 2012
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