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The FDA classifies the data as insufficient rather than confirming harm
And Professor Tricia Tan, from the department of metabolism, digestion and reproduction at Imperial College London, told the outlet that these drugs should not be used during pregnancy. Animal studies did show that the animal babies born to animals who were given these medications had problems. This guidance is reiterated by Novo Nordisk, which told PEOPLE it is recommended to discontinue Wegovy in women at least 2 months before a planned pregnancy due to the long washout period for semaglutide. The rep added there may be potential risks to the fetus from exposure to semaglutide during pregnancy
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Still, the clinical conversation should focus on whether this type of support fits the patients full health picture
A study in *Clinical Therapeutics* found that patients on GLP-1 therapy experienced 1525% variability in levothyroxine levels compared to their baseline, even when taking the same dose
