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Its use is limited to research settings due to the lack of FDA approval
Jun 29 2021;10(13)doi:10.3390/jcm10132896
The absence of preservatives makes sterile water safer for direct tissue contact and reduces the risk of irritation or adverse reactions
Also, patients should be warned about the danger of taking folic acid in place of vitamin B 12 , because the former may prevent anemia but allow progression of subacute combined degeneration
Pickart and Thaler isolated it from human serum in 1973 and characterized it as a tripeptide that prolongs survival of normal liver cells and stimulates growth in neoplastic liver tissue 17
