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Pathogenic variants in genes encoding transporters and channels found in the DCT are associated with several diseases in humans including Bartter syndrome, Gitelman syndrome, familial hyperkalemic hypertension, EAST syndrome ( E pilepsy, A taxia, S ensorineural deafness, and salt-wasting renal T ubulopathy), and hereditary hypomagnesemias
Even so, the growing prevalence of GLP-1s has reportedly influenced the way consumers think about portion sizing, even if they arent taking the medications themselves
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Sleep apnea The SURMOUNT-OSA trial demonstrated that tirzepatide reduced the severity of obstructive sleep apnea significantly, with some patients achieving complete resolution
