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Donor evaluation is essential: temporary diffuse shedding can reduce apparent density, while diffuse unpatterned alopecia can make the donor area intrinsically unsafe

Melanotan II was investigated clinically but never reached approval

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This specific localization within the GCL is of profound clinical relevance, as retinal ganglion cells are the primary neurons that degenerate in glaucoma and are also critically affected during the early neurodegenerative stages of diabetic retinopathy [38, 39]