Semaglutide and orforglipron are pure GLP-1 agonists
Shi Y, Wang H, Su Z, Chen J, Xue Y, Wang S et al (2010) Differentiation imbalance of Th1/ Th17 in peripheral blood mononuclear cells might contribute to pathogenesis of Hashimotos thyroiditis: differentiation imbalance of Th1/Th17 contribute to pathogenesis of HT
Other Ingredients: Vegetable Cellulose Capsule, Organic Rice Extract Blend and Silica
Note: GLP-1 medications carry a boxed warning regarding the risk of thyroid C-cell tumors based on animal studies
The foundational chemistry was reported by Al-Obeidi, Castrucci, Hadley, and Hruby in J Med Chem 1989, describing the design rationale based on molecular dynamics modeling [2]