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Our study is first to demonstrate novel molecular mechanisms involved in the sensitization of PTC cells to ferroptosis inducer- we show that RSL3, a potent direct GPX4 inhibitor, effectively reduces the viability of thyroid cancer lines with various mutational backgrounds compared to HThF control cell line in a dose-dependent manner
Yeast Culture, Vitamins (Vitamin E Supplement, Niacin Supplement, d-Calcium Pantothenate, Riboflavin Supplement, Vitamin A Supplement, Vitamin D3 Supplement, Vitamin B12 Supplement, Pyridoxine Hydrochloride, Biotin, Thiamine Mononitrate, Folic Acid), Fish Oil (preserved with Mixed Tocopherols)